You asked: Would you feel alright if your employer lied to you if they felt like it was in their best interest?

Of course not. But I can also tell you that 9 times out of 10, they absolutely do.  I was hired by a company that knew they were going out of business and I didn't find out until a week before it happened. "Oh yeah...btw, you won't have a job next week because we're shutting things down. We knew when we hired you, but figured you wouldn't take the job if you knew..."  Really...? Thanks...

Well, I could be idealistic and say they shouldn't have lied. Or I could be realistic and realize that if they needed someone to get the job done, they absolutely had to lie, otherwise, no one would have accepted the job.

The other case in which I would absolutely lie is when the Nazi is knocking on my door asking if I'm hiding a Jew in my house.  Or any similar situation...